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Bioelectromagnetism
FIGURE 5.7 Time course of LHY, PRR7, and GI relative expression in Arabidopsis thaliana grown under GMF
and NNMF in long day conditions (LD). LHY (A) and PRR7 (B) under LD conditions always show increased gene
expressions when exposed to NNMF, with respect to GMF. GI (C) always shows a reduced gene expression under
NNMF, when compared to GMF. In all plots, white boxes indicate the light phase, whereas black boxes indicate the
dark phase. (Modifed from Agliassa and Mafei (2019).)
modifcations that lead to the production of proteins involved in fowering control, and proteomic stud
ies are necessary to better asses the role of NNMF on fowering control.
Plant endogenous clock consists of self-sustained interlocked transcriptional/translational feedback
loops whose oscillation regulates many circadian processes, including gene expression. Its free-running
rhythm can be entrained by external cues, which can infuence all clock parameters. Te quantitative
expression (qRT-PCR) of three clock genes (LHY, GI, and PRR7) in time-course experiments under long
day conditions in A. thaliana seedlings exposed to GMF and NNMF conditions reveals that reduction
of GMF to NNMF prompted a signifcant increase of the gene expression of LHY and PRR7, whereas an
opposite trend was found for GI gene expression. Exposure of Arabidopsis to NNMF altered clock gene
amplitude, regardless of the presence of light, by reinforcing the morning loop (Figure 5.7). Terefore,
these results are consistent with the existence of a plant magnetoreceptor that afects the Arabidopsis
endogenous clock (Agliassa and Mafei, 2019).
To comprehensively investigate the infuence of the GMF on A. thaliana photoreceptor signaling,
wild-type (WT) Arabidopsis seedlings and photoreceptor-defcient mutants (cry1cry2, phot1, phyA, and
phyAphyB) were exposed to NNMF and GMF under diferent light wavelengths. For the frst time, the
infuence of the GMF on photoreceptor signaling both under red and blue light was shown (Agliassa
et al., 2018b). Overall, despite the absence of a GMF-induced changes in Arabidopsis seedling photo
morphogenesis, a signifcant GMF-dependent diferential shoot/root regulation of genes expressed fol
lowing photoreceptor activation afer 72 hours exposure to GMF with respect to NNMF conditions was
found. In particular, under blue light, the GMF regulation of gene expression appears to be partially
dependent on cryptochrome activation, which is enhanced in terms of increased cry1 phosphoryla
tion and cry2 degradation. Under red light, the GMF-dependent regulation of light-induced genes is
partially mediated by phyA and phyB, whose activation is altered by cry1, cry2, and phot1 in their inac
tive form (Figure 5.8). If we consider that the red light response to GMF is not limited to phyA and
phyB (Jeong et al., 2016), the contribution of other phytochromes to this response cannot be excluded.
Terefore, despite the involvement of cryptochrome, and the possibility of a cryptochrome-based RPM,
magnetoreception in Arabidopsis appears to be diferent from the mechanism thought to be responsible
for the ability of migratory songbirds to detect the direction of the GMF. Tese results suggest also
that other processes besides photoreceptor activation could be probably involved in GMF perception
(Agliassa et al., 2018b).
Te reduction of the GMF to NNMF afects the accumulation of metals in plant tissues, mainly iron
(Fe) and zinc (Zn) content, while the content of other metals such as copper (Cu) and manganese (Mn)